Polar amino acids

Clearly polar amino acids:

Less polar amino acids, or indifferent amino acids:

Polar amino acids are those with side-chains that prefer to reside in an aqueous (i.e. water) environment. For this reason, one generally finds these amino acids exposed on the surface of a protein.

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Please cite: M.J. Betts, R.B. Russell. Amino acid properties and consequences of subsitutions.
In Bioinformatics for Geneticists, M.R. Barnes, I.C. Gray eds, Wiley, 2003.